Synthesis of Tjipanazole E

C24H20Cl2N2O5
Principal investigator | Jeffrey T. Kuethe |
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Publication year | 2003 |
Synthesis type | Total |
Number of steps | 6 (linear) |
References |
Part 1 of 1
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DMAP,
Boc2O
THF
RT, 3 h, 100%




CH(EtO)2CH2NMe2
AcOH
Reflux, 105 min, 71%


Aliquat 336,
KOH
H2O, MTBE
RT, 12 h, 89%

H2,
Pd(OH)2
1 atm
H2O
RT, 2 h, 87%
