Synthesis of Methoxatin

C14H6N2O8
Principal investigator | Steven M. Weinreb |
---|---|
Publication year | 1981 |
Synthesis type | Total |
Number of steps | 14 (linear) |
References |
Part 1 of 1
+
+

- (CH2NMe2)2 , n-BuLi
- CO2
Hexane(s)
RT, 18 h, 66%


- KOH
- HCl
H2O
60% (2 steps)







HNO3
H2SO4
-20 °C, 1.5 min, 60%


NaH
THF
RT, 2 h, 92%



HNO3,
AgO
THF
RT, 10 min, 60%

LiOH
H2O, THF
RT, 5 h, 75%
