Synthesis of Triquinacene

C10H10
Principal investigator | James M. Cook |
---|---|
Publication year | 1989 |
Synthesis type | Total |
Number of steps | 8 (linear) |
References |
Part 1 of 1
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CH2N2
CH2Cl2
RT, 2 h, 90%

Allyl-I,
KH
DMF
-58 to -25 °C, 6 h

HCl
AcOH, H2O
Reflux, 90 min, 90% (2 steps)

- O3
- Me2S
EtOAc
-58 °C, 81%


BH3.THF
THF
0 °C, 16 h, 93%

HMPA
Reflux, 2 d, 80%
