Synthesis of Quinine
|Principal investigator||Paul Rabe|
|Number of steps||3 (linear)|
Part 1 of 1
RT, 24 h, 55%
"The starting material (quinotoxine) was obtained from the degradation of natural quinine."
Reflux, 10 min, 88%
See the Hofmann-Löffler-Freytag Reaction
Reflux, 2 h, 5%
"(-)-Quinine was selectively cristallized (as a tartrate salt) from the resulting four diastereoisomers."