Sandmeyer Reaction

Schematic representation of the Sandmeyer Reaction.
Mechanism of the Sandmeyer Reaction
Mechanism of the Sandmeyer Reaction
Sample reactions
intermediate structure
CuBr, H2SO4, HBr, NaNO2
AcOH, H2O
0 to 80 °C, 14 h, 92%
intermediate structure
intermediate structure
H2SO4, KI, NaNO2
H2O, MeCN
0 °C to RT, 15 min
intermediate structure
intermediate structure
HCl, NaNO2
H2O
0 °C to RT, , 74%
intermediate structure