Saegusa-Ito Oxidation

Schematic representation of the Saegusa-Ito Oxidation.
Mechanism of the Saegusa-Ito Oxidation
Mechanism of the Saegusa-Ito Oxidation
Original publication
Review
Sample reactions
intermediate structure
Pd(OAc)2
MeCN
RT, 4 h, 84% (2 steps)
intermediate structure
intermediate structure
Pd(OAc)2
MeCN
RT, 3 h, 88% (2 steps)
intermediate structure
intermediate structure
O2, Pd(OAc)2
DMSO
RT, 18 h, 90% (2 steps)
intermediate structure
intermediate structure
O2, Pd(OAc)2
DMSO
RT, 18 h, 84% (2 steps)
intermediate structure
intermediate structure
Pd(OAc)2, 1,4-Benzoquinone
MeCN
RT, 6 h, 80% (2 steps)
"The yield was 89 % brsm."
intermediate structure
intermediate structure
Pd2(dba)3.CHCl3, Diallyl carbonate
MeCN
RT, 12 h, 90% (2 steps)
intermediate structure
intermediate structure
Pd(OAc)2
DMSO, MeCN
RT, 16 h, 82% (2 steps)
intermediate structure
intermediate structure
O2, Pd(OAc)2
DMSO
80 °C, 15 h, 91%
intermediate structure
intermediate structure
O2, Pd(OAc)2
DMSO
80 °C, 20 h, 75%
intermediate structure