Noyori Asymmetric Hydrogenation

Schematic representation of the Noyori Asymmetric Hydrogenation.
Mechanism of the Noyori Asymmetric Hydrogenation
Mechanism of the Noyori Asymmetric Hydrogenation
Sample reactions
intermediate structure
H2, [RuI2(p-cymene)]2, (R)-BINAP
CH2Cl2, MeOH
40 °C, 24 h, 95%
intermediate structure
intermediate structure
H2
MeOH
RT, , 93%
intermediate structure