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Named reactions

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Penicillin V

Chemical structure of Penicillin_V
C17H20N2O5S
Author John C. Sheehan
Publication year 1957
Synthesis type Total synthesis
Number of steps 5 (linear)
References

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
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Chemical structure
NaOAc
EtOH, H2O
RT, 10 h, 24 %

Also isolated was the C1'-epimer (30 % yield) which was equilibrated in refluxing pyridine.
Chemical structure
NH2NH2
Dioxane , H2O
RT, 24 h, 82 %
Chemical structure
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Chemical structure
Et3N
CH2Cl2
0 °C, 22 h, 70 %
Chemical structure
HCl
CH2Cl2
0-5 °C, 30 h, 94 %
Chemical structure
DCC, NaOH
Dioxane , H2O
RT, 33 h, 11 %
Chemical structure

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