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Named reactions

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Mycophenolic Acid

Chemical structure of Mycophenolic_Acid
C17H20O6
Author Rick L. Danheiser
Publication year 1986
Synthesis type Total synthesis
Number of steps 9 (linear)
Reference

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
NaBH4
EtOH
0 °C to RT, 30 min
Chemical structure
TBSCl, Et3N, DMAP
CH2Cl2
RT, 20 h
Chemical structure
K2CO3
MeOH
RT, 24 h, 83% (2 steps)
Chemical structure + Chemical structure
  1. n-BuLi, MsCl
  2. Li2CuCl4
THF
-78 °C to RT, 8 h, 91%
Chemical structure + Chemical structure
Sealed tube
PhH
120 °C, 14 h, 73%

See the Danheiser Benzannulation
Chemical structure
Br2, t-BuNH2
PhMe
-78 to 5 °C, 4 h, 85%
Chemical structure
  1. MeLi.LiBr
  2. t-BuLi
  3. CO2
THF
-78 to 0 °C, 2.5 h
Chemical structure
HCl
MeOH, H2O
Reflux, 4.5 h, 70% (2 steps)
Chemical structure
CrO3, H2SO4
Acetone, H2O
-30 °C, 5 h, 61%

See the Jones Oxidation
Chemical structure

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