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Named reactions

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Search synthesis

Bikaverin

Chemical structure of Bikaverin
C20H14O8
Author Derek H. R. Barton
Publication year 1975
Synthesis type Total synthesis
Number of steps 11 (linear)
References

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
MeCN, Me3N+Bn HO-
Dean-Stark
PhH
Reflux, 2 h, 82%

See the Aldol Condensation
Chemical structure
H2, Pd/C
1 atm
EtOH
RT, 93%
Chemical structure + Chemical structure
HCl, ZnCl2
PhNO2
RT, 4 d, 70%

See the Houben-Hoesch Reaction
Chemical structure
(CO2Et)2, NaOEt
PhH
RT, 4 h, 40%

See the Claisen Condensation
Chemical structure
TsOH
PhH
Reflux, 2 h, 90%
Chemical structure
Me2SO4, K2CO3
Acetone
Reflux, 2 h, 90%

See the Williamson Ether Synthesis
Chemical structure
KOH
EtOH
RT, 24 h
Chemical structure
SOCl2
PhH, DMF
Reflux, 3 h
Chemical structure
BF3.OEt2
CH2Cl2
RT to reflux, ON, 77% (3 steps)

See the Friedel-Crafts Acylation
Chemical structure
K2Cr2O7
AcOH
RT, 2.5 h, 58%
Chemical structure
LiI
MeCOt-Bu
Reflux, 5 h, 80%
Chemical structure

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