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"This paper is dedicated to Professor Fèlix Serratosa on the occasion of his 65th birthday."

Chemical structure of Hirsutene
Author Andrew E. Greene
Publication year 1990
Synthesis type Formal synthesis
Number of steps 16 (linear)

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Chemical structure
Chemical structure
Mg, ZnCl2, CuCN
57 %
Chemical structure
74 %
Chemical structure
55 %

See the Pauson-Khand Reaction
Chemical structure
80 %
Chemical structure
85 %
Chemical structure

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2.0 % (11 steps)

See: Tetrahedron Lett. 1976, 17, 195.
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