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Named reactions

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Hirsutene

Chemical structure of Hirsutene
C15H24
Author Michel Franck-Neumann
Publication year 1989
Synthesis type Formal synthesis
Number of steps 10 (linear)
Reference

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
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Chemical structure
CuBr.Me2S
THF
-78 °C, 15 h

See the Michael Addition
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HCl
THF, H2O
40 °C, 24 h, 84 % (2 steps)

See the Aldol Addition
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BzCl
Pyr
RT, 4 h, 90 %
Chemical structure
TsOH, Morpholine
PhEt
Reflux, 24 h, 91 %
Chemical structure
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Chemical structure
Et2O
RT, 24 h, 40 %
Chemical structure
HI
PhMe, H2O
RT, 4 h, 85 %
Chemical structure
H2, Pd/C, Et3N
MeOH
RT, 12 h, 91 %
Chemical structure
Li
NH3
30 %
Chemical structure
HCrO3Cl.Pyr
CH2Cl2
RT, 30 min, 100 %
Chemical structure

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98 % (1 step)

See: Tetrahedron 1985, 41, 4765.
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