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Named reactions

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Search synthesis

Hirsutene

Chemical structure of Hirsutene
C15H24
Author Janine Cossy
Publication year 1987
Synthesis type Total synthesis
Number of steps 9 (linear)
References

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
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Chemical structure
Pd(OAc)2, P(Oi-Pr)3
PhMe
Reflux, 20 h, 60%
Chemical structure
CH2N2, Pd(OAc)2
Et2O
0 °C, 30 min, 99%
Chemical structure
H2, PtO2, NaOAc
1 atm
AcOH
RT, 20 h, 82%
Chemical structure + Chemical structure
KH
DME
-70 to 0 °C, 3 h, 71%
Chemical structure
LiAlH4
Et2O
0 °C, 60 min, 90%
Chemical structure
KH
1,3-Diaminopropane
0 °C, 60 min, 86%

See the Alkyne Zipper Reaction
Chemical structure
HCrO3Cl.Pyr
3 Å MS
CH2Cl2
RT, 4 h, 96%

Selectivity : 83:17 β/α
Chemical structure
Et3N
MeCN
RT, 2.5 h, 58%
Chemical structure
MeMgBr, (Ph3P)2NiCl2
PhH
Reflux, 66 h, 35%
Chemical structure

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