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Thiarubrine B
C13H8S2
| Author | Eric Block |
|---|---|
| Publication year | 1994 |
| Synthesis type | Total synthesis |
| Number of steps | 12 (linear) |
| Reference |
Browse hundreds of other total syntheses.
Part 1 of 1
n-BuLi, S8, BnBr
Et2O
-78 °C to RT, ON, 100 %
-78 °C to RT, ON, 100 %
n-Bu4N+ F-
THF, H2O
RT, 2.5 h, 96 %
RT, 2.5 h, 96 %
Ph3SnH, Pd(PPh3)4, Et3B
PhMe, Hexane(s)
-30 °C to RT, ON, 56 %
-30 °C to RT, ON, 56 %
I2
CH2Cl2
0 °C, 2 h, 97 %
0 °C, 2 h, 97 %
I2
CH2Cl2
0 °C, 2 h, 95 %
0 °C, 2 h, 95 %
+ 
n-Bu4N+ F-
THF
RT, 3 h, 86 %
RT, 3 h, 86 %
KOH, I2
MeOH
-35 to 0 °C, 17 % (2 steps)
-35 to 0 °C, 17 % (2 steps)
