Synarchive logo
Google+ Facebook Twitter RSS Feed
Support this website
Synarchive is free but requires a lot of work. If you enjoy and find it useful, please support us by making a donation.
Named reactions

Get references and more from over 225 named organic chemical reaction

Go to the named reaction index

Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

Go to the protecting groups index

Search synthesis

Cephalosporin C1

Chemical structure of Cephalosporin_C1
C16H21N3O8S
Author Robert B. Woodward
Publication year 1966
Synthesis type Total synthesis
Number of steps 16 (linear)
Reference

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
COCl2, Pyr
CH2Cl2, t-BuOH
Chemical structure
CH2N2
Chemical structure
+
Chemical structure
105 °C, 45 h
Chemical structure
Pb(OAc)4
PhH
Reflux, 2 h
Chemical structure
NaOAc
MeOH
Reflux, 24 h
Chemical structure
MsCl, i-Pr2NEt
DMF
Chemical structure
NaN3
H2O
Chemical structure
Al(Hg)
MeOH
-15 °C, 24 h
Chemical structure
i-Bu3Al
PhMe
Chemical structure
+
Chemical structure
80 °C, 16 h

See the Michael Addition
Chemical structure
CF3CO2H
RT, 2.5 h
Chemical structure
+
Chemical structure
DCC
THF
Chemical structure
DCC, Cl3CCH2OH
CH2Cl2, Pyr

See the Steglich Esterification
Chemical structure
BH3.THF
THF
Chemical structure
Ac2O
Pyr
RT, 72 h
Chemical structure
Zn
AcOH
0 °C, 2.5 h
Chemical structure

Report an error in this part

comments powered by Disqus
homepage - authors - molecules - named reactions - protecting groups - advanced search - contact
© 2011-2017 SynArchive