Synarchive logo
Google+ Facebook Twitter RSS Feed
Support this website
Synarchive is free but requires a lot of work. If you enjoy and find it useful, please support us by making a donation.
Named reactions

Get references and more from over 229 named organic chemical reaction

Go to the named reaction index

Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

Go to the protecting groups index

Search synthesis

Nupharamine

Chemical structure of Nupharamine
C15H25NO2
Author Franklin A. Davis
Publication year 2006
Synthesis type Formal synthesis
Number of steps 10 (linear)
Reference

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
+
Chemical structure
Ti(OEt)4
CH2Cl2
RT, 5 h, 92%
Chemical structure
2-Butanone, TMS2NK
Et2O
-78 °C, 90 min, 84%

Selectivity : >99:01 dr
See the Mannich Reaction
Chemical structure
CF3CO2H
MeOH
0 °C, 2 h
Chemical structure + Chemical structure
MgSO4
CH2Cl2
RT, 2 h, 86% (2 steps)
Chemical structure
TsOH
PhH
60 °C, 4 h, 74%

See the Mannich Reaction
Chemical structure
(CH2SH)2, BF3.OEt2
CH2Cl2
0 °C to RT, 2 h, 93%
Chemical structure
Ni (Raney)
EtOH
Reflux, 2 h, 78%
Chemical structure

Report an error in this part

Remaining...
(3 steps)

See: J. Org. Chem. 1999, 64, 3736.
comments powered by Disqus
homepage - authors - molecules - named reactions - protecting groups - advanced search - contact
© 2011-2017 SynArchive