Synthesis of Taiwaniaquinol B

Structure of Taiwaniaquinol B

C20H28O4

Principal investigatorDirk Trauner
Publication year2006
Synthesis typeTotal
Number of steps 6 (linear)
References
Part 1 of 1
intermediate structure
NBS
DMF
RT, 42 h, 98%
intermediate structure + intermediate structure
n-BuLi
Et2O
-25 °C to RT, 105 min, 89%
intermediate structure
Dess-Martin Periodinane
CH2Cl2, Pyr
RT, 5 min, 90%
intermediate structure
TMSOTf
MeNO2
105 °C, 65 min, 70%
intermediate structure
BCl3
CH2Cl2
0 °C, 15 min, 90%
intermediate structure
(NH4)2Ce(NO3)6, Na2S2O4
MeCN, CH2Cl2, H2O
0 °C, 4 h, 51%
intermediate structure