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Named reactions

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Strychnine

Chemical structure of Strychnine
C21H22N2O2
Author Graham J. Bodwell
Publication year 2002
Synthesis type Formal synthesis
Number of steps 12 (linear)
Reference

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
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Chemical structure
s-BuOH
Reflux, 4 d, 100%
Chemical structure
AllylBr, KOH
DMF
RT, 3 h, 91%
Chemical structure
  1. 9-BBN
  2. Pd(PPh3)4, Cs2CO3, H2O
THF
0 °C to reflux, 60 h, 65%

See the Suzuki Coupling
Chemical structure
ClCO2Me, TMS2NNa
THF
-78 °C to RT, 4 h, 96%
Chemical structure
PhNEt2
Reflux, 60 min, 100%

See the Diels-Alder Reaction
Chemical structure
NaBH4
PhH, CF3CO2H
0 °C to RT, 12 h, 100%
Chemical structure
H2Cr2O7.2Pyr, Celite ®
CH2Cl2
RT, 3 d, 30%
Chemical structure
TMSI
CHCl3
Reflux, 6 h, 100%
Chemical structure

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See : J. Org. Chem. 1994, 59, 2685; J. Org. Chem. 1993, 58, 7490.
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