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Named reactions

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Protecting Groups

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Search synthesis

Oseltamivir

Chemical structure of Oseltamivir
C16H28N2O4
Author Elias J. Corey
Publication year 2006
Synthesis type Total synthesis
Number of steps 12 (linear)
Reference

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
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Chemical structure
Reagent structure
RT, 30 h, 97%

Selectivity : 99:01 er
See the Diels-Alder Reaction
Chemical structure
NH3
CF3CH2OH
40 °C, 5 h, 100%
Chemical structure
TMSOTf, Et3N
Pentane
0 °C to RT, 2 h
Chemical structure
I2
Et2O, THF
0 °C, 3 h, 84% (2 steps)
Chemical structure
Boc2O, Et3N, DMAP
CH2Cl2
RT, 4 h, 99%
Chemical structure
DBU
THF
Reflux, 12 h, 96%
Chemical structure
NBS, AIBN
CCl4
Reflux, 2 h, 95%

See the Wohl-Ziegler Reaction
Chemical structure
Cs2CO3
EtOH
RT, 25 min, 100%
Chemical structure
N-Bromoacetamide, SnBr4
MeCN
-40 °C, 4 h, 75%
Chemical structure
TMS2NK, n-Bu4N+ Br-
DME
-20 °C, 10 min, 82%
Chemical structure
3-Pentanol, Cu(OTf)2
0 °C, 12 h, 61%
Chemical structure
H3PO4
EtOH
Chemical structure

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