Synarchive logo
Google+ Facebook Twitter RSS Feed
Support this website
Synarchive is free but requires a lot of work. If you enjoy and find it useful, please support us by making a donation.
Named reactions

Get references and more from over 229 named organic chemical reaction

Go to the named reaction index

Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

Go to the protecting groups index

Search synthesis

Mesembrine

Chemical structure of Mesembrine
C17H23NO3
Author Maurice Shamma
Publication year 1965
Synthesis type Total synthesis
Number of steps 20 (linear)
Reference

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
1,3-Butadiene
PhMe

See the Diels-Alder Reaction
No yield given.
Chemical structure
NaOEt, HCl
EtOH, H2O
0 °C to RT, 2.5 h

See the Nef Reaction
Chemical structure
H2, Pd/C
3 atm
EtOH
70% (2 steps)
Chemical structure
AllylBr, NaH
PhH
Reflux, 10 h, 95%
Chemical structure
LiAlH4
Et2O
RT, 2 h, 70%
Chemical structure
Ac2O
Pyr
Reflux, 2 h, 92%
Chemical structure
OsO4, NaIO4
Dioxane , H2O
RT, ON, 79%

See the Lemieux-Johnson Oxidation
Chemical structure
AgNO3, KOH
EtOH, H2O
RT, 2 h, 93%

See the Tollens Oxidation
Chemical structure
(COCl)2
PhH
RT, 2 h
Chemical structure
MeNH2
PhH
0 °C, 93% (2 steps)
Chemical structure
LiAlH4
THF, Dioxane
Reflux, 17 h, 90%
Chemical structure
HCO2Et
Et3N
Reflux, ON, 92%
Chemical structure
Na2Cr2O7, H2SO4
Acetone, H2O
80%

See the Jones Oxidation
Chemical structure
PhNMe3+ Br3-
THF
RT, 19 h
Chemical structure
CaCO3
DMF
Reflux, 2 h, 79% (2 steps)
Chemical structure
NaOCl
Pyr, H2O
0 °C, 60 min, 90%

See the Michael Addition
Chemical structure
Cr(OAc)2, NaOAc
Acetone, AcOH
40%
Chemical structure
NaBH4
EtOH
RT, ON, 95%
Chemical structure
O2, Pt
EtOAc
RT, 3 d
Chemical structure
HCl
EtOH, H2O
Reflux, 4 h, 50% (2 steps)

See the Michael Addition
Chemical structure

Report an error in this part

comments powered by Disqus
homepage - authors - molecules - named reactions - protecting groups - advanced search - contact
© 2011-2017 SynArchive