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Named reactions

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Search synthesis

Cubane

Chemical structure of Cubane
C8H8
Author Philip E. Eaton
Publication year 1964
Synthesis type Total synthesis
Number of steps 15 (linear)
References

Browse hundreds of other total syntheses.

Part 1 of 1
Chemical structure
NBS
CCl4

See the Wohl-Ziegler Reaction
Chemical structure
Br2
Pentane, CH2Cl2
0 to 10 °C
Chemical structure
Et2NH
Et2O
-20 °C, 40 % (3 steps)

See the Diels-Alder Reaction
Chemical structure
(CH2OH)2, TsOH
PhH
Reflux
Chemical structure
HCl
H2O
85 % (2 steps)
Chemical structure
MeOH
95 %
Chemical structure
KOH
H2O
Reflux, 95 %

See the Favorskii Rearrangement
Chemical structure
SOCl2
Chemical structure
t-BuOOH, Pyr
Et2O
95 % (2 steps)
Chemical structure
Cumene
152 °C, 55 %
Chemical structure
H2SO4
H2O
95 %
Chemical structure
KOH
H2O
Reflux, 55 %

See the Favorskii Rearrangement
Chemical structure
SOCl2
Chemical structure
t-BuOOH
Et2O
98 % (2 steps)
Chemical structure
Diisopropylbenzene
150 °C, 30 %
Chemical structure

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