Synarchive logo
Google+ Facebook Twitter RSS Feed
Support this website
Synarchive is free but requires a lot of work. If you enjoy and find it useful, please support us by making a donation.
Named reactions

Get references and more from over 229 named organic chemical reaction

Go to the named reaction index

Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

Go to the protecting groups index

Search synthesis

Methoxymethyl acetal (MOM)

Protection

 
Reagents
Solvents
Temperature
Time
Yield
MeOCH2Cl, i-Pr2NEt
CH2Cl2
0 °C to RT
3 h - ON
85-98 %
MeOCH2Cl, NaH, n-Bu4N+ I-
DMF
0 °C to RT
24 - 72 h
71-91 %
MeOCH2Cl, NaH
DMF
0 °C - RT
2 h
74-96 %

Deprotection

 
Reagents
Solvents
Temperature
Time
Yield
HCl
MeOH, H2O
-12 °C - RT
7 h - 3 d
65-85 %
HBr
CH2Cl2
0 °C
2 h
80 &
I2
MeOH
RT
2 h
66 %
homepage - authors - molecules - named reactions - protecting groups - advanced search - contact
© 2011-2017 SynArchive