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Named reactions

Get references and more from over 225 named organic chemical reaction

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Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

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Search synthesis

[2-(Trimethylsilyl)ethoxy]methyl acetal (SEM)

Protection

 
Reagents
Solvents
Temperature
Time
Yield
TMS(CH2)2OCH2Cl, KH, 18-Crown-6
THF
RT
5 h
84 %

Deprotection

 
Reagents
Solvents
Temperature
Time
Yield
n-Bu4N+ F-
HMPA
50 °C
12 h
60 %
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