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Named reactions

Get references and more from over 225 named organic chemical reaction

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Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

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Trifluoroacetamide

Protection

 
Reagents
Solvents
Temperature
Time
Yield
(CF3CO)2O, Pyr
CH2Cl2
0 °C - RT
12.5 h
74 %
(CF3CO)2O, K2CO3
CHCl3
RT
30 min
79 %

Deprotection

 
Reagents
Solvents
Temperature
Time
Yield
NaOMe
CH2Cl2, MeOH
RT
60 min
82 %
K2CO3
MeOH, H2O
Reflux
30 min
100 %
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