4-Methoxybenzenesulfonamide

4-Methoxybenzenesulfonamide scheme

Protection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • 4-Methoxybenzenesulfonyl chloride i-Pr2NEt DMAP
    CH2Cl2
    0 °C - RT
    24 h
    81 %
    intermediate structure
    4-Methoxybenzenesulfonyl chloride, i-Pr2NEt, DMAP
    CH2Cl2
    0 °C to RT, 24 h, 81%
    intermediate structure

Deprotection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • Na.Anthracene
    DME
    -30 °C - RT
    13.5 h
    90 %
    intermediate structure
    Na.Anthracene
    DME
    -30 °C to RT, 13.5 h, 90%
    intermediate structure