Diethyl acetal

Diethyl acetal scheme

Protection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • HC(OEt)3 TsOH
    EtOH
    Reflux
    6 h
    95 %
    intermediate structure
    HC(OEt)3, TsOH
    EtOH
    Reflux, 6 h, 95%
    intermediate structure

Deprotection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • HCl
    THF H2O
    RT
    25 min
    100 %
    intermediate structure
    HCl
    THF, H2O
    RT, 25 min, 100%
    intermediate structure