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Named reactions

Get references and more from over 229 named organic chemical reaction

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Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

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Methyl ether

Protection

 
Reagents
Solvents
Temperature
Time
Yield
MeI, NaH
THF
0 °C - RT
60 min
96 %
MeI, KH
THF
RT - Reflux
2 h
90 %
MeI, KH, 18-Crown-6
THF
0 °C - RT
2 d
77 %
MeI, Ag2O, CaSO4
RT
20 h
96 %
MeOTf, 2,6-Di-tert-butylpyridine
CH2Cl2
RT
40 h
85 %

Deprotection

 
Reagents
Solvents
Temperature
Time
Yield
TMSCl, NaI
MeCN, H2O
40 °C
15 h
97 %
TMSI
MeCN
60 °C
48 h
95 %
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