Methoxypropyl acetal (MOP)

Methoxypropyl acetal (MOP) scheme

Protection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • TsOH 2-Methoxypropene
    THF
    0 °C
    10 min
    100 %
    info
    intermediate structure
    TsOH, 2-Methoxypropene
    THF
    0 °C, 10 min, 100%
    intermediate structure
  • Pyr.TsOH 2-Methoxypropene
    CH2Cl2
    RT
    5 min
    97 %
    info
    intermediate structure
    Pyr.TsOH, 2-Methoxypropene
    CH2Cl2
    RT, 5 min, 97%
    intermediate structure

Deprotection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • Pyr.TsOH
    CH2Cl2 THF
    RT
    3 h
    92 %
    info
    intermediate structure
    Pyr.TsOH
    CH2Cl2, THF
    RT, 3 h, 92%
    intermediate structure