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Named reactions

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Protecting Groups

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Methoxymethyl acetal (MOM)

Protection

 
Reagents
Solvents
Temperature
Time
Yield
MeOCH2Cl, i-Pr2NEt
CH2Cl2
RT - 50 °C
4 - 18 h
90-98 %
CH2(OMe)2, P2O5
CHCl3
RT
4 h
86 %
MeOCH2Cl, i-Pr2NEt, DMAP
CH2Cl2
0 °C - RT
16 h
71-97 %

Deprotection

 
Reagents
Solvents
Temperature
Time
Yield
HCl
MeOH, H2O
RT
3 - 8 h
89-93 %
HBr
MeCN, H2O
RT
2 h
95 %
TMSBr
CH2Cl2
0 °C
30 min
100 %
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