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Named reactions

Get references and more from over 225 named organic chemical reaction

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Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

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Benzoate (Bz)

Protection

 
Reagents
Solvents
Temperature
Time
Yield
BzCl, Pyr
CH2Cl2
RT
3 h
96 %
BzCl
Pyr
RT - 70 °C
4 - 24 h
78-90 %
BzCl, Et3N, DMAP
CH2Cl2
0 °C - RT
30 min
82 %

Deprotection

 
Reagents
Solvents
Temperature
Time
Yield
K2CO3
MeOH
RT
60 min - 2 h
94-95 %
K2CO3
MeOH, THF
RT
2 h
81 %
KOH
EtOH
RT
20 min
80 %
KCN
EtOH
0 °C
3 h
68 %
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