2,2,2-Trichloroethyl carbonate (Troc)

2,2,2-Trichloroethyl carbonate (Troc) scheme

Protection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • ClCO2CH2CCl3 Pyr
    CH2Cl2
    RT
    3 h
    94 %
    intermediate structure
    ClCO2CH2CCl3, Pyr
    CH2Cl2
    RT, 3 h, 94%
    intermediate structure

Deprotection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • Zn
    AcOH H2O
    RT
    16 h
    84 %
    intermediate structure
    Zn
    AcOH, H2O
    RT, 16 h, 84%
    intermediate structure