Synarchive logo
Google+ Facebook Twitter RSS Feed
Support this website
Synarchive is free but requires a lot of work. If you enjoy and find it useful, please support us by making a donation.
Named reactions

Get references and more from over 225 named organic chemical reaction

Go to the named reaction index

Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

Go to the protecting groups index

Search synthesis

Trimethylsilane (TMS)

Protection

 
Reagents
Solvents
Temperature
Time
Yield
TMSCl, i-Pr2NLi
THF
-78 °C - RT
3 h
92 %

Deprotection

 
Reagents
Solvents
Temperature
Time
Yield
n-Bu4N+ F-
THF
0 °C - RT
20 min - 3 h
86-87 %
n-Bu4N+ F-
THF, H2O
RT
2.5 h
96 %
homepage - authors - molecules - named reactions - protecting groups - advanced search - contact
© 2011-2017 SynArchive