di-tert-Butyl dioxasilinane

di-tert-Butyl dioxasilinane scheme

Protection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • t-Bu2Si(OTf)2 2,6-Lutidine
    CH2Cl2
    0 °C
    60 min
    91%
    intermediate structure
    t-Bu2Si(OTf)2, 2,6-Lutidine
    CH2Cl2
    0 °C, 60 min, 91%
    intermediate structure

Deprotection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • Pyr.HF Pyr
    THF H2O
    RT
    3 h
    91%
    intermediate structure
    Pyr.HF, Pyr
    THF, H2O
    RT, 3 h, 91%
    intermediate structure