Weiss-Cook Condensation

Schematic representation of the Weiss-Cook Condensation.
Mechanism of the Weiss-Cook Condensation
Mechanism of the Weiss-Cook Condensation
Original publication
Tetrahedron Lett.. 1968, 9, 4885. J. Org. Chem.. 1976, 41, 1903.
Reviews
Aldrichimica Acta. 1992, 25, 43. Tetrahedron. 1981, 37, 4521. Tetrahedron. 1991, 47, 3665.
Sample reactions
info
intermediate structure intermediate structure
K2CO3, NaHCO3
H2O, MeOH
RT, 3 d, 45%
intermediate structure
info
intermediate structure
NaHCO3
H2O, MeOH
RT, 12 h, 92%
intermediate structure