Sample reactions
intermediate structure
Dimethyl malonate, Pd(PPh3)4, KOt-Bu
THF
50 °C, 3 h
intermediate structure
intermediate structure intermediate structure
NaH, Pd2(dba)3, Ph3P
THF
RT, , 91%
intermediate structure
intermediate structure
Pd(PPh3)4, K2CO3
MeCN
Reflux, , 83%
intermediate structure
intermediate structure intermediate structure
Pd2(dba)3, (2-Furyl)3P
PhMe
RT, 20 min, 86%
intermediate structure
intermediate structure intermediate structure
Pd2(dba)3.CHCl3
DMF
0 °C, 36 h, 80%
intermediate structure