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Named Reactions
Protecting Groups
Pinacol Rearrangement
Mechanism of the Pinacol Rearrangement
Original publication
Liebigs Ann.. 1860, 114, 54.
Reviews
Comp. Org. Syn.. 1991, 3, 721.
J. Org. Chem.. 2003, 68, 7143.
Q. Rev. Chem. Soc.. 1960, 14, 357.
Sample reactions
info
SnCl4
CH2Cl2
0 °C to RT, 14.5 h, 32%
info
HCl
AcOH
,
H2O
Reflux, 5 min
info
Al2O3
,
AgBF4
CCl4
-20 °C, 21 h, 52%
info
Et3N
,
MsCl
-30 to 4 °C, 73 h, 98%