Lombardo Methylenation

Schematic representation of the Lombardo Methylenation.
Mechanism of the Lombardo Methylenation
Mechanism of the Lombardo Methylenation
Sample reactions
intermediate structure
Zn, TiCl4, CH2I2, PbCl2
THF
72%
intermediate structure
intermediate structure
CH2Br2, Zn, TiCl4
THF, CH2Cl2
-40 to 0 °C, 20 h, 98%
intermediate structure