Japp-Klingemann Reaction

Schematic representation of the Japp-Klingemann Reaction.
Mechanism of the Japp-Klingemann Reaction
Mechanism of the Japp-Klingemann Reaction
Original publication
Ber. Dtsch. Chem. Ges.. 1887, 20, 2942. Ber. Dtsch. Chem. Ges.. 1887, 20, 3284. Ber. Dtsch. Chem. Ges.. 1887, 20, 3398.
Review
Org. React.. 1959, 10, 1143.
Sample reactions
info
intermediate structure intermediate structure
HCl, NaNO2
H2O, MeOH
0 °C, 8 h, 80%
intermediate structure
info
intermediate structure
NaBH4, Pyr, MeOH, PhN2+ BF4-
H2O
-10 °C, , 70%
intermediate structure