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Named Reactions
Protecting Groups
Ireland-Claisen Rearrangement
Mechanism of the Ireland-Claisen Rearrangement
Original publication
J. Am. Chem. Soc.. 1972, 94, 5897.
J. Org. Chem.. 2008, 73, 2803.
Reviews
Acc. Chem. Res.. 1977, 10, 1423.
Aldrichimica Acta. 1992, 26, 17.
Tetrahedron. 2002, 58, 2905.
Sample reactions
info
i-Pr2NLi
,
TBSCl
HMPA
,
THF
-78 °C, 2.5 h
info
i-Pr2NLi
,
TBSCl
THF
-78 °C to Reflux, 4.5 h
info
CHCl3
Reflux, 5 h