Hofmann Elimination

Schematic representation of the Hofmann Elimination.
Mechanism of the Hofmann Elimination
Mechanism of the Hofmann Elimination
Sample reactions
intermediate structure
NaOH
H2O
180 °C, 60 min, 38%
intermediate structure
intermediate structure
Me2SO4, NaOH
H2O
Reflux, 2.5 h, 84%
intermediate structure