Eschenmoser Sulfide Contraction

Schematic representation of the Eschenmoser Sulfide Contraction.

Mechanism of the Eschenmoser Sulfide Contraction

Mechanism of the Eschenmoser Sulfide Contraction

Original publication	Helv. Chim. Acta. 1971, 54, 710.
Review

Sample reactions

intermediate structure

P(OEt)3

Xylene(s)

125 °C, , 85% (2 steps)

intermediate structure

intermediate structure

P(CH2CH2CN)3

MeNO2, CF3CO2H

intermediate structure

intermediate structure

Ph3P

CH2Cl2, CF3CO2H

intermediate structure

intermediate structure

intermediate structure

NaHCO3

CH2Cl2

Reflux

intermediate structure