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Protecting Groups
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Named Reactions
Protecting Groups
Doebner-Miller Reaction
Mechanism of the Doebner-Miller Reaction
Original publication
Ber. Dtsch. Chem. Ges.. 1881, 14, 2812.
Review
Chem. Heterocycl. Compd.. 2006, 42, 701.
Sample reactions
info
TsOH
,
Cu(OAc)2
CHCl3
Reflux, 8.5 h, 50%
info
HCl
CH2Cl2
RT, 17 h, 90%
info
HCl
CH2Cl2
RT, 24 h, 95%