Dess-Martin Oxidation

Schematic representation of the Dess-Martin Oxidation.
Mechanism of the Dess-Martin Oxidation
Mechanism of the Dess-Martin Oxidation
Original publication
Review
Sample reactions
intermediate structure
Dess-Martin Periodinane
CH2Cl2
0 °C to RT, 3 h, 85% (2 steps)
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 3 h, 90%
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
0 °C, 90 min
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
0 °C, 20 min
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 3.5 h
intermediate structure
intermediate structure
Dess-Martin Periodinane, Pyr
CH2Cl2
RT, 8 h, 94%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 2 h
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 2 h
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3, H2CN+Me2 I-, Et3N
CH2Cl2
RT, ON, 97%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, ON, 77%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 60 min, 92%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 60 min
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
-40 to 10 °C, 90 min, 74%
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
0 °C to RT, 6 h, 89%
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
0 to 25 °C, 4 h, 96%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
4 °C to RT, 3 h, 88%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CHCl3
RT, 60 min, 96%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 2 h
intermediate structure
intermediate structure
SeO2, Dess-Martin Periodinane
Dioxane
75 °C to RT, 4.5 h, 58%
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
0 °C, 60 min, 59% (2 steps)
"The yield was 73 % brsm."
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
0 °C to RT, 2 h, 96%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 60 min, 90%
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
RT, 2 h, 80% (2 steps)
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
RT, 2 h, 87% (2 steps)
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
4 °C to RT, 25 min, 90%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
0 °C to RT, 3.5 h
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
0 °C, 4.5 h, 90%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
0 °C to RT, 35 min, 69% (3 steps)
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
0 °C, 60 min, 91%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
0 °C to RT, 10 h, 84% (2 steps)
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 3 min, 90%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2, Pyr
RT, 5 min, 90%
intermediate structure
intermediate structure
Dess-Martin Periodinane, Pyr
CH2Cl2
13 °C to RT, 25 min, 90%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 30 min, 91%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2, H2O
intermediate structure
intermediate structure
Dess-Martin Periodinane, NaHCO3
CH2Cl2
RT, 2.5 h, 77% (3 steps)
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 4 h, 80% (2 steps)
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 2 h
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 30 min, 95%
intermediate structure
intermediate structure
Dess-Martin Periodinane
CH2Cl2
RT, 20 min, 86% (2 steps)
intermediate structure