Corey-Nicolaou Macrolactonization

Schematic representation of the Corey-Nicolaou Macrolactonization.
Mechanism of the Corey-Nicolaou Macrolactonization
Mechanism of the Corey-Nicolaou Macrolactonization
Sample reactions
intermediate structure
PhMe
110 °C, , 70% (3 steps)
intermediate structure