Collins Oxidation

Schematic representation of the Collins Oxidation.
Mechanism of the Collins Oxidation
Mechanism of the Collins Oxidation
Original publication
Review
Sample reactions
intermediate structure
CrO3.2Pyr
CH2Cl2
0 °C
intermediate structure
intermediate structure
CrO3.2Pyr
CH2Cl2
-45 to -22 °C, 60 min, 76%
intermediate structure
intermediate structure
CrO3.2Pyr
CH2Cl2
RT, , 78%
intermediate structure
intermediate structure
CrO3.2Pyr
CH2Cl2
RT, 15 min, 100%
intermediate structure
intermediate structure
CrO3.2Pyr
74%
intermediate structure
intermediate structure
CrO3.2Pyr
60% (2 steps)
intermediate structure