Bischler-Napieralski Reaction

Schematic representation of the Bischler-Napieralski Reaction.
Mechanism of the Bischler-Napieralski Reaction
Mechanism of the Bischler-Napieralski Reaction
Sample reactions
intermediate structure
POCl3
Reflux, 2 h
intermediate structure
intermediate structure
Ac2O, HCl
HCO2H, H2O
RT to 55 °C, 16 h, 63%
intermediate structure
intermediate structure
POCl3
MeCN
Reflux, 70 min
intermediate structure