Acyloin Condensation

Schematic representation of the Acyloin Condensation.
Mechanism of the Acyloin Condensation
Mechanism of the Acyloin Condensation
Sample reactions
intermediate structure
Na
Et2O, MeOH, NH3
-78 °C, 15 min, 48%
intermediate structure
intermediate structure
TMSCl, Na
PhMe
Reflux, 16 h, 82%
intermediate structure