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Named reactions

Get references and more from over 225 named organic chemical reaction

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Protecting Groups

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Wolff Rearrangement

Wolff Rearrangement

Mechanism of the Wolff Rearrangement

Reference

Original reference Angew. Chem. Int. Ed. 1975, 14, 32.
Wikipedia link
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Sample reactions

This reaction is from the synthesis of Chlorophyll A by Robert B. Woodward. Show me the full synthesis.

Reactant structure
NH2NH2.H2O, NaOH
Reaction arrow head
Triethylene glycol
Reflux, 2 h
63-83 &
Product structure

This reaction is from the synthesis of Pentacycloanammoxic Acid by Elias J. Corey. Show me the full synthesis.

Reactant structure
Et3N
Reaction arrow head
MeOH
RT, 3 h
72 %
Product structure

This reaction is from the synthesis of Cyanocobalamin by Robert B. Woodward. Show me the full synthesis.

Reactant structure
Ag2O
Reaction arrow head
MeOH
65 °C
69 % (3 steps)
Product structure

This reaction is from the synthesis of Dodecahedrane by Horst Prinzbach. Show me the full synthesis.

Reactant structure + Reactant structure
NaHCO3
Reaction arrow head
THF, H2O
RT, 2 h
90 %
Product structure

This reaction is from the synthesis of Alkaloid GB 13 by Lewis N. Mander. Show me the full synthesis.

Reactant structure
TMS2NH
Reaction arrow head
THF
RT, 6 h
68 % (3 steps)
Product structure
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