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Named reactions

Get references and more from over 229 named organic chemical reaction

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Protecting Groups

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Sonogashira Coupling

Sonogashira Coupling

Mechanism of the Sonogashira Coupling

Reference

Original reference Tetrahedron Lett. 1975, 16, 4467.
Wikipedia link
Organic chemistry portal link


Sample reactions

This reaction is from the synthesis of Ginkgolide B by Elias J. Corey. Show me the full synthesis.

Reactant structure + Reactant structure
Pd(PPh3)4, n-PrNH2, CuI
Reaction arrow head
PhH
16 °C, 4 h
76%
Product structure

This reaction is from the synthesis of Strychnine by Peter C. Vollhardt. Show me the full synthesis.

Reactant structure
Trimethylsilylacetylene, Pd(PPh3)2Cl2, CuI
Reaction arrow head
Et3N
RT, 60 min
98%
Product structure

This reaction is from the synthesis of Thiarubrine A by Masato Koreeda. Show me the full synthesis.

Reactant structure
VinylBr, Pd(PPh3)4, CuI, Et3N
Reaction arrow head
PhMe
RT, 4.5 h
41%
Product structure

This reaction is from the synthesis of Thiarubrine B by Eric Block. Show me the full synthesis.

Reactant structure
Trimethylsilylacetylene, Pd(PPh3)2Cl2, Et2NH, CuI
Reaction arrow head
PhH
RT, 38 h
86%
Product structure

This reaction is from the synthesis of Thiarubrine B by Eric Block. Show me the full synthesis.

Reactant structure + Reactant structure
Pd(PPh3)2Cl2, Et2NH, CuI
Reaction arrow head
PhH
RT, 40 h
57%
Product structure

This reaction is from the synthesis of Thiarubrine B by Eric Block. Show me the full synthesis.

Reactant structure
VinylBr, Pd(PPh3)2Cl2, Et2NH, CuI
Reaction arrow head
PhH
RT, 16 h
70%
Product structure

This reaction is from the synthesis of Virantmycin by Ralph A. Raphael. Show me the full synthesis.

Reactant structure + Reactant structure
Pd(PPh3)2Cl2, CuI
Reaction arrow head
Et2NH
RT, 16 h
94%
Product structure
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