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Named reactions

Get references and more from over 225 named organic chemical reaction

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Protecting Groups

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Johnson-Corey-Chaykovsky Reaction

Johnson-Corey-Chaykovsky Reaction

Mechanism of the Johnson-Corey-Chaykovsky Reaction

References

Original reference J. Am. Chem. Soc. 1962, 84, 867.J. Am. Chem. Soc. 1961, 83, 417.
Wikipedia link
Organic chemistry portal link


Sample reactions

This step is from the synthesis of Colchicine by David A. Evans. Show me the full synthesis.

Reactant structure
Me3SO+ I-, NaH
Reaction arrow head
DMSO
0 °C, 3 h
91 %
Product structure

This step is from the synthesis of Colchicine by Martin G. Banwell. Show me the full synthesis.

Reactant structure
Me3SO+ I-, NaH
Reaction arrow head
DMSO
RT, 7 h
54 %
Product structure

This step is from the synthesis of Cristatic Acid, Methyl Ester by Alois Fürstner. Show me the full synthesis.

Reactant structure + Reactant structure
t-BuLi
Reaction arrow head
THF
-78 °C, 10 min
62 %
Product structure

This step is from the synthesis of Taxol by Samuel J. Danishefsky. Show me the full synthesis.

Reactant structure
Me3S+ I-, TMS2NK
Reaction arrow head
THF
0 °C, 2.5 h
99 %
Product structure

This step is from the synthesis of Phyllanthocin by David R. Williams. Show me the full synthesis.

Reactant structure
Me3S+ I-, NaH
Reaction arrow head
DMSO
RT, 30 min
92 %
Product structure

This step is from the synthesis of Morphine by Larry E. Overman. Show me the full synthesis.

Reactant structure
Me2S=CH2
Reaction arrow head
91 %
Product structure

This step is from the synthesis of Strychnine by Martin E. Kuehne. Show me the full synthesis.

Reactant structure
Me3S+ I-, n-BuLi
Reaction arrow head
THF
-20 °C to RT, 4 h
70 %
Product structure

This step is from the synthesis of Hirsutene by Tarun K. Sarkar. Show me the full synthesis.

Reactant structure
NaH, DMSO, TMSI
Reaction arrow head
THF
0 °C to RT, 2 h
61 %
Product structure
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